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Uterine fibroids and incidence of depression, anxiety and self-directed violence: a cohort study
Background Depression and anxiety are prevalent among women with uterine fibroids (UF). ...
Graphical depiction of longitudinal study designs in health care databases
Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has become a ...
Actionable Real-World Evidence to Improve Health Outcomes and Reduce Medical Spending Among Risk-Stratified Patients with Diabetes
Background: Type 2 diabetes mellitus (T2DM) is a chronic condition with a high economic ...
Effectiveness of the Single-Dose Ad26.COV2.S COVID Vaccine
Importance Vaccination against the SARS-CoV-2 virus is critical to control the pandemic. ...
Outcomes associated with oral anticoagulants plus antiplatelets in patients with newly diagnosed atrial fibrillation
Importance Patients with nonvalvular atrial fibrillation at risk of stroke should receive ...
SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes
Importance: In the absence of evidence of clinical utility, the United States' Centers ...
Treatment Patterns and Healthcare Resource Utilization Among Newly Diagnosed Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, and Hidradenitis Suppurativa
Introduction Psoriasis (PSO), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), ...
Healthcare Resource Utilization and Related Costs in Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype: A US Claims Database Analysis
Introduction We aimed to describe healthcare resource utilization (HCRU) patterns and ...
Variable selection for confounding adjustment in high-dimensional covariate spaces when analyzing healthcare databases
Background: Data-adaptive approaches to confounding adjustment may improve performance ...
Comparison of External Control Arm Critiques in Regulatory and Health Technology Assessment of Oncology Submissions
Objectives: The development of accelerated approval programs for high morbidity and unmet ...
Erratum: high-dimensional propensity score adjustment in studies of treatment effects using health care claims data
In the article titled “High-dimensional Propensity Score Adjustment in Studies of ...
Measuring prevalence and incidence of chronic conditions in claims and electronic health record databases
Background Health care databases are natural sources for estimating prevalence and ...
Annual health care resource utilization and cost among type 2 diabetes patients with newly recognized chronic kidney disease within a large US administrative claims database
BACKGROUND: Chronic kidney disease (CKD) is one of the most common complications of type ...
[REPEAT] Reproducibility of real-world evidence studies using clinical practice data to inform regulatory and coverage decisions. Nature Communications
Studies that generate real-world evidence on the effects of medical products through ...
Disease frequency, patient characteristics, comorbidity outcomes and immunosuppressive therapy in systemic sclerosis and systemic sclerosis-associated interstitial lung disease: a US cohort Study
Objectives To investigate prevalence estimates and incidence rates (IRs) for SSc and ...
Impact of season and other factors on initiation, discontinuation and switching of systemic drug therapy in patients with psoriasis - a retrospective study
This study investigated whether systemic drug prescribing for psoriasis varies by season ...
Predictors of cardio-kidney complications and treatment failure in patients with chronic kidney disease and type 2 diabetes treated with SGLT2is
Background: Clinical practice guidelines recommend sodium-glucose co-transporter 2 ...
High unmet treatment needs in patients with chronic kidney disease and type 2 diabetes: real-world evidence from a US claims database
Background Chronic kidney disease (CKD), a serious complication of type 2 diabetes (T2D) ...
High-dimensional propensity scores for empirical covariate selection in secondary database studies
Real-world evidence used for regulatory, payer, and clinical decision-making requires ...
Organized structure of real-world evidence best practices: moving from fragmented recommendations to comprehensive guidance
Decision-makers have become increasingly interested in incorporating real-world evidence ...
Key Learnings from ICER’s Real World Evidence Reassessment Pilot
Health technology assessment (HTA) agencies are considering adopting a lifecycle approach ...
Safety of Intravenous Pantoprazole Sodium in Pediatric Patients Aged 1 Month to < 1 Year: A Real-World Retrospective Cohort Study
Objective To estimate the incidence rates (IR) of prespecified outcomes of interest in ...
Using Healthcare Databases to Replicate Trial Findings for Supplemental Indications: Adalimumab in Patients with Ulcerative Colitis
Regulators wish to understand whether real world evidence can be used for secondary ...
Prevalence and Incidence of Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype in the United States Estimated in a Large Claims Database Analysis
Introduction Many fibrosing interstitial lung diseases (ILDs) develop a chronic ...