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Real‐world evidence on bariatric surgery and cardiovascular benefits using electronic health record data: A lesson in bias
Aim To reproduce and correct studies on bariatric surgery and the reduction in major ...
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Use of systemic immunomodulating medications in pregnant women with atopic dermatitis: a nationwide US study
No abstract available
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Transparency and reproducibility of observational cohort studies using large healthcare databases.
The scientific community and decision-makers are increasingly concerned about ...
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Healthcare resource utilization, costs and treatment associated with myasthenia gravis exacerbations among patients with myasthenia gravis in the US: A retrospective analysis of claims data
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Visualizations throughout pharmacoepidemiology study planning, implementation, and reporting
Transparency is increasingly promoted to instill trust in nonrandomized studies using ...
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Durability of the Single-Dose Ad26.COV2.S Vaccine in the Prevention of COVID-19 Infections and Hospitalizations in the US Before and During the Delta Variant Surge
Importance Vaccination against the SARS-CoV-2 virus is critical to control the pandemic. ...
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Empirical assessment of case‐based methods for identification of drugs associated with acute liver injury in the French National Healthcare System database (SNDS)
Purposes Drug induced acute liver injury (ALI) is a frequent cause of liver failure. ...
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Post-Authorization Safety Studies of Medicinal Products: The PASS, Chapter 3.4 Big Data
Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in ...
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Association of remdesivir with lower mortality in hospitalized adults with Covid-19 in the United States
Importance SARS-CoV-2, which causes COVID-19, poses considerable morbidity and mortality ...
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Opioid dispensing patterns after oocyte retrieval
Objective: To study opioid dispensing patterns following oocyte retrieval. Design: ...
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Incidence of lower extremity amputations among patients with type 1 and type 2 diabetes in the United States from 2010 to 2014
Aim To compare the incidence of lower extremity amputation (LEA) among patients with type ...
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Cardiovascular Burden of Narcolepsy Disease (CV-BOND): a real-world evidence study.
Study Objectives Narcolepsy is associated with cardiovascular risk factors; however, the ...
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Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection
Importance Understanding the effect of serum antibodies to severe acute respiratory ...
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Chronic kidney disease progression among patients with type 2 diabetes identified in US administrative claims: a population cohort study
Background Chronic kidney disease (CKD), one of the most common complications of type 2 ...
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Renin-Angiotensin-Aldosterone-System inhibitor use in patients with COVID-19 infection and prevention of serious events: a cohort study in commercially insured patients in the US
Objectives There is lack of clarity regarding the role of angiotensin receptor blockers ...
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Learning from the past to advance tomorrow's real world evidence: what demonstration projects have to teach us.
Regulators, health technology assessment (HTA) agencies, and payers are actively ...
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A Descriptive Cohort Study of Drug Utilization Patterns Among Patients Hospitalized With Coronavirus Disease 2019 in the United States, January 2021–February 2022
Background There is a dearth of drug utilization studies for coronavirus disease 2019 ...
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Healthcare Resource Utilization and Baseline Characteristics of Patients With Generalized Pustular Psoriasis: Real-World Results From a Large US Database of Multiple Commercial Medical Insurers
Background: Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin ...
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Clinical Burden of Concomitant Joint Disease in Psoriasis: A US-Linked Claims and Electronic Health Records Database Analysis
Background Few studies have evaluated the clinical burden of concomitant joint disease in ...
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Clinical characteristics and healthcare resource utilization in patients with generalized pustular psoriasis: real-world evidence from a large claims-based dataset
Background: Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin ...
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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
INTRODUCTION The emergence of three lethal coronaviruses in <20 years and the urgency ...
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First Maintenance Therapy for Chronic Obstructive Pulmonary Disease: Retrospective Analyses of US and UK Healthcare Databases
Introduction Inhaled corticosteroids (ICS) are often prescribed inappropriately alongside ...
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Healthcare utilization of patients with hereditary angioedema treated with lanadelumab and subcutaneous C1-inhibitor concentrate
Background: New hereditary angioedema (HAE) treatments have become available in recent ...
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Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative.
Background: Regulators are evaluating the use of noninterventional real-world evidence ...