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Evidence Hub

Jun 5, 2025

When Clinical Trials Stall, Evidence Shouldn't: How Generative Models Restore Power to Under-Enrolled Studies

Lucy Mosquera, MS, and Natalie Schibell, MPH Understanding the Impact of Incomplete ...
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Jun 3, 2025

Real-World Evidence at Every Stage – How Aetion Powers the Drug Development Lifecycle

Natalie Schibell, MPH and Ashley Jaksa, MPH
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May 29, 2025

Built for Scientific Rigor: How Aetion Delivers Methodologically Defensible Real-World Evidence

Debra E. Irwin, PhD, MSPH, Amanda Kong, DrPH, and Natalie Schibell, MPH
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May 27, 2025

Reflections on SUSTAIN-HTA: Strengthening Process Readiness for Real-World Evidence in Health Technology Assessment

Real-world evidence (RWE) is becoming foundational in how health technology assessment ...
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May 21, 2025

Analytic Flexibility in Focus: Using Aetion Measure Library and Substantiate in Discover

Natalie Schibell, MPH and Jaquelyn Bilog
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May 14, 2025

New Release: Aetion Generate 3.7 Enhances Privacy-First Real-World Data Transformation

At Aetion®, we believe privacy should never hinder evidence generation. With version 3.7 ...
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May 7, 2025

Real-World Evidence in Health Technology Reassessments: A New Era in Evidence-Based Decision-Making

Ashley Jaksa, MPH, and Patrick Arena, PhD A Lifecycle Approach to Evaluating the Value of ...
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May 5, 2025

From Framework to Formulary: Real-World Evidence in Action for Managed Care

Ashley Jaksa, MPH and Natalie Schibell, MPH
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Apr 30, 2025

Feature Spotlight: Streamlining Propensity Score Adjustment with Substantiate

Nataile Schibell, MPH and Pippa Hodgkins
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Apr 14, 2025

Aetion® Generate Expands with Replicate, Protect, and Enhance

Purpose-Built Solutions to Secure, Scale, and Strengthen Real-World Data Utility
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Apr 9, 2025

Real-World Evidence at Scale: Aetion® Launches in AWS Marketplace

Healthcare decisions depend on defensible, timely evidence. From regulatory filings to ...
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Apr 8, 2025

Case Study: Use Aetion Generate to accelerate access to clinical trial data

Our case study, "Use Aetion® Generate to Accelerate Access to Clinical Trial Data,” ...
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Apr 2, 2025

Safety and effectiveness of MVA-BN vaccination against mpox in at-risk individuals in Germany (SEMVAc and TEMVAc)

As mpox continues to pose a global public health challenge, real-world evidence (RWE) ...
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Apr 2, 2025

Increasing the Utility of Real-World Data to Inform Public Health Decision Making Through a US-based Private–Public Partnership

The urgency of the COVID-19 pandemic highlighted the need for rapid, reliable real-world ...
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Mar 27, 2025

Ensuring Accuracy in Real-World Epidemiology: How Aetion® Substantiate Delivers Reliable Prevalence and Incidence Estimates

Ashley Jaksa, MPH, Natalie Schibell, MPH, and Pippa Hodgkins Aetion® Substantiate: A ...
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Mar 24, 2025

Quantifying Disease Burden with Confidence: Prevalence and Incidence Analytics in Aetion® Discover

Natalie Schibell, MPH, Pippa Hodgkins, and Abby Case Aetion® Discover: A Solution for ...
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Mar 20, 2025

Whitepaper: Synthetic Data in Healthcare: Solving Privacy, Scarcity, and Bias Challenges

While real-world data (RWD) offers invaluable insights for research and decision-making, ...
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Mar 17, 2025

Real-World Evidence in Action: Supporting Regulatory Advancements in Robotic-Assisted Surgery

The National Evaluation System for Health Technology (NEST) Coordinating Center was ...
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Mar 13, 2025

De-Identification in Healthcare: The Legal and Strategic Imperative for Global Compliance

Lucy Mosquera, MS, and Natalie Schibell, MPH The regulatory landscape for real-world data ...
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Mar 7, 2025

Decision-Ready Evidence, Any Data Model, No Compromises

Real-world data (RWD) exists in multiple formats—claims, electronic health records, ...
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Mar 5, 2025

Behind the Evidence: Conversations at the Intersection of Product and Science

Q&A with Brenna Kirk, Associate Director, Science Collaboration between Aetion’s ...
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Mar 3, 2025

Shaping the Future of IBD Drug Development with Real-World Data

Michelle Skornicki, MPH, Natalie Schibell, MPH, and Rohan Shah Inflammatory bowel disease ...
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Feb 27, 2025

Elevating Cohort Analysis with Population Exploration in Substantiate

Natalie Schibell, MPH and Pippa Hodgkins As healthcare systems navigate increasingly ...
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Feb 26, 2025

Real-World Evidence in Medical Device Approvals: Strengthening the Path to Regulatory Success

Expanding the Role of Real-World Evidence in Medical Device Regulation Regulatory ...
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