Skip to content

Evidence Hub

Publication
Mar 24, 2024

An evaluation of the replicability of analyses using synthetic health data

This paper published in Scientific Reports describes a study evaluating the replicability ...
Start Reading
Publication
Nov 1, 2023

Evaluating the Utility and Privacy of Synthetic Breast Cancer Clinical Trial Data Sets

This paper published in the Journal of Clinical Oncology: Clinical Cancer Informatics ...
Start Reading
Publication
Aug 1, 2023

Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Modeling Studies: Development and Validation.

The reporting of machine learning (ML) prognostic and diagnostic modeling studies is ...
Start Reading
Publication
Jul 13, 2023

A comparison of synthetic data generation and federated analysis for enabling international evaluations of cardiovascular health

Our recent article in Scientific Reports entitled, A comparison of synthetic data ...
Start Reading
Publication
May 1, 2023

Practical Synthetic Data Generation

This book published by O'Reilly is an introduction to synthetic data generation ...
Start Reading
Publication
May 1, 2023

A method for generating synthetic longitudinal health data

Getting access to administrative health data for research is difficult and time-consuming ...
Start Reading
Publication
Feb 14, 2023

Prescription opioid fills following surgical abortion

Objective To characterize opioid fills after surgical abortion among US ...
Start Reading
Publication
Feb 14, 2023

Use of an EHR to inform an administrative data algorithm to categorize inpatient COVID-19 severity.

Importance Algorithms for classification of inpatient COVID-19 severity are necessary for ...
Start Reading
Publication
Feb 14, 2023

Selective serotonin reuptake inhibitor use and perioperative bleeding and mortality in patients undergoing coronary artery bypass grafting: a cohort study

Introduction Several small studies have reported inconsistent findings about the safety ...
Start Reading
Publication
Feb 14, 2023

Early real-world experience with emicizumab and concomitant factor VIII replacement products in adult male people with Hemophilia A without inhibitors

Aims To assess real-world use of emicizumab in adult people with hemophilia A (PwHA) ...
Start Reading
Publication
Feb 14, 2023

Categorization of COVID-19 severity to determine mortality risk

Purpose Algorithms for classification of inpatient COVID-19 severity are necessary for ...
Start Reading
Publication
Feb 14, 2023

Real-world comparative effectiveness of mRNA-1273 and BNT162b2 vaccines among immunocompromised adults identified in administrative claims data in the United States

Introduction Head-to-head studies comparing COVID-19 mRNA vaccine effectiveness in ...
Start Reading
Publication
Feb 14, 2023

Treatment effectiveness in a rare oncology indication: lessons from an external control cohort study

Real-world data (RWD) reflecting patient treatment in routine clinical practice can be ...
Start Reading
Publication
Feb 14, 2023

Describing characteristics and treatment patterns of patients hospitalized with COVID-19 by race and ethnicity in a national RWD during the early months of the pandemic

Objective To describe differences by race and ethnicity in treatment patterns among ...
Start Reading
Publication
Feb 14, 2023

A case for synthetic data in regulatory decision-making in Europe

Regulators are faced with many challenges surrounding health data usage, including ...
Start Reading
Publication
Feb 14, 2023

Uterine fibroids and incidence of depression, anxiety and self-directed violence: a cohort study

Background Depression and anxiety are prevalent among women with uterine fibroids (UF). ...
Start Reading
Publication
Feb 14, 2023

Graphical depiction of longitudinal study designs in health care databases

Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has become a ...
Start Reading
Publication
Feb 14, 2023

Actionable Real-World Evidence to Improve Health Outcomes and Reduce Medical Spending Among Risk-Stratified Patients with Diabetes

Background: Type 2 diabetes mellitus (T2DM) is a chronic condition with a high economic ...
Start Reading
Publication
Feb 14, 2023

Effectiveness of the Single-Dose Ad26.COV2.S COVID Vaccine

Importance Vaccination against the SARS-CoV-2 virus is critical to control the pandemic. ...
Start Reading
Publication
Feb 14, 2023

Outcomes associated with oral anticoagulants plus antiplatelets in patients with newly diagnosed atrial fibrillation

Importance Patients with nonvalvular atrial fibrillation at risk of stroke should receive ...
Start Reading
Publication
Feb 14, 2023

SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes

Importance: In the absence of evidence of clinical utility, the United States' Centers ...
Start Reading
Publication
Feb 14, 2023

Treatment Patterns and Healthcare Resource Utilization Among Newly Diagnosed Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, and Hidradenitis Suppurativa

Introduction Psoriasis (PSO), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), ...
Start Reading
Publication
Feb 14, 2023

Healthcare Resource Utilization and Related Costs in Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype: A US Claims Database Analysis

Introduction We aimed to describe healthcare resource utilization (HCRU) patterns and ...
Start Reading
Publication
Feb 14, 2023

Variable selection for confounding adjustment in high-dimensional covariate spaces when analyzing healthcare databases

Background: Data-adaptive approaches to confounding adjustment may improve performance ...
Start Reading