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Augmenting Insufficiently Accruing Oncology Clinical Trials Using Generative Models: Validation Study
Recruitment shortfalls are a major reason clinical trials fail, often leading to ...
Safety and effectiveness of MVA-BN vaccination against mpox in at-risk individuals in Germany (SEMVAc and TEMVAc)
As mpox continues to pose a global public health challenge, real-world evidence (RWE) ...
Increasing the Utility of Real-World Data to Inform Public Health Decision Making Through a US-based Private–Public Partnership
The urgency of the COVID-19 pandemic highlighted the need for rapid, reliable real-world ...
Linking clinical trial participants to their U.S. real-world data through tokenization: A practical guide
While electronic health record data integration is common in clinical trials, the ...
Advancing Principled Pharmacoepidemiologic Research to Support Regulatory and Healthcare Decision Making: The Era of Real-World Evidence
The increasing availability of rich healthcare datasets, advanced data extraction ...
Evaluating Real-World Use of Botulinum Toxins for Cervical Dystonia, Blepharospasm, and Hemifacial Spasm
Movement disorders like cervical dystonia, blepharospasm, and hemifacial spasm can ...
Understanding Clinical Profiles and Treatment Approaches in Chronic Sialorrhea: A Real-World Study
Chronic sialorrhea, an underdiagnosed and poorly understood condition marked by excessive ...
Use of transportability methods for real-world evidence generation: A review of current applications
A recent study investigated whether and how statistical techniques, referred to as ...
Calibrating Observational Health Record Data Against a Randomized Trial
A first-of-its-kind cross-industry initiative, the Aetion CARE Initiative brings together ...
Evaluating the Effectiveness of a Third COVID-19 Vaccine Dose in Immunocompromised Adults
As the immunocompromised population faces heightened risks from COVID-19, understanding ...
Hypertension Risk in Narcolepsy Patients Using Sodium Oxybate: A Real-World Study
Managing narcolepsy often requires the use of specialized medications, but understanding ...
Understanding the Economic Burden of RSV-Associated Hospitalizations in Adults
Respiratory syncytial virus (RSV) poses significant health risks, particularly for older ...
Comparing the Effectiveness of a Third COVID-19 Vaccine Dose in Older Adults
As the COVID-19 pandemic continues to evolve, the importance of booster doses in ...
The potential role of real-world evidence in Centers for Medicare & Medicaid Services’ future price negotiations: Recommendations for a robust framework
In this article, authors Ashley Jaksa (VP, Scientific Strategy & Partnerships, ...
An evaluation of the replicability of analyses using synthetic health data
This paper published in Scientific Reports describes a study evaluating the replicability ...
Evaluating the Utility and Privacy of Synthetic Breast Cancer Clinical Trial Data Sets
This paper published in the Journal of Clinical Oncology: Clinical Cancer Informatics ...
Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Modeling Studies: Development and Validation.
The reporting of machine learning (ML) prognostic and diagnostic modeling studies is ...
A comparison of synthetic data generation and federated analysis for enabling international evaluations of cardiovascular health
Our recent article in Scientific Reports entitled, A comparison of synthetic data ...
Practical Synthetic Data Generation
This book published by O'Reilly is an introduction to synthetic data generation ...
A method for generating synthetic longitudinal health data
Getting access to administrative health data for research is difficult and time-consuming ...
Prescription opioid fills following surgical abortion
Objective To characterize opioid fills after surgical abortion among US ...
Use of an EHR to inform an administrative data algorithm to categorize inpatient COVID-19 severity.
Importance Algorithms for classification of inpatient COVID-19 severity are necessary for ...
Selective serotonin reuptake inhibitor use and perioperative bleeding and mortality in patients undergoing coronary artery bypass grafting: a cohort study
Introduction Several small studies have reported inconsistent findings about the safety ...
Early real-world experience with emicizumab and concomitant factor VIII replacement products in adult male people with Hemophilia A without inhibitors
Aims To assess real-world use of emicizumab in adult people with hemophilia A (PwHA) ...