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Evaluating Real-World Use of Botulinum Toxins for Cervical Dystonia, Blepharospasm, and Hemifacial Spasm
Movement disorders like cervical dystonia, blepharospasm, and hemifacial spasm can ...
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Understanding Clinical Profiles and Treatment Approaches in Chronic Sialorrhea: A Real-World Study
Chronic sialorrhea, and underdiagnosed and poorly understood condition marked by ...
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Use of transportability methods for real-world evidence generation: A review of current applications
A recent study investigated whether and how statistical techniques, referred to as ...
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Calibrating Observational Health Record Data Against a Randomized Trial
A first-of-its-kind cross-industry initiative, the Aetion CARE Initiative brings together ...
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Evaluating the Effectiveness of a Third COVID-19 Vaccine Dose in Immunocompromised Adults
As the immunocompromised population faces heightened risks from COVID-19, understanding ...
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Hypertension Risk in Narcolepsy Patients Using Sodium Oxybate: A Real-World Study
Managing narcolepsy often requires the use of specialized medications, but understanding ...
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Understanding the Economic Burden of RSV-Associated Hospitalizations in Adults
Respiratory syncytial virus (RSV) poses significant health risks, particularly for older ...
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Comparing the Effectiveness of a Third COVID-19 Vaccine Dose in Older Adults
As the COVID-19 pandemic continues to evolve, the importance of booster doses in ...
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The potential role of real-world evidence in Centers for Medicare & Medicaid Services’ future price negotiations: Recommendations for a robust framework
In this article, authors Ashley Jaksa (VP, Scientific Strategy & Partnerships, ...
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An evaluation of the replicability of analyses using synthetic health data
This paper published in Scientific Reports describes a study evaluating the replicability ...
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Evaluating the Utility and Privacy of Synthetic Breast Cancer Clinical Trial Data Sets
This paper published in the Journal of Clinical Oncology: Clinical Cancer Informatics ...
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Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Modeling Studies: Development and Validation.
The reporting of machine learning (ML) prognostic and diagnostic modeling studies is ...
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A comparison of synthetic data generation and federated analysis for enabling international evaluations of cardiovascular health
Our recent article in Scientific Reports entitled, A comparison of synthetic data ...
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Practical Synthetic Data Generation
This book published by O'Reilly is an introduction to synthetic data generation ...
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A method for generating synthetic longitudinal health data
Getting access to administrative health data for research is difficult and time-consuming ...
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Prescription opioid fills following surgical abortion
Objective To characterize opioid fills after surgical abortion among US ...
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Use of an EHR to inform an administrative data algorithm to categorize inpatient COVID-19 severity.
Importance Algorithms for classification of inpatient COVID-19 severity are necessary for ...
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Selective serotonin reuptake inhibitor use and perioperative bleeding and mortality in patients undergoing coronary artery bypass grafting: a cohort study
Introduction Several small studies have reported inconsistent findings about the safety ...
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Early real-world experience with emicizumab and concomitant factor VIII replacement products in adult male people with Hemophilia A without inhibitors
Aims To assess real-world use of emicizumab in adult people with hemophilia A (PwHA) ...
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Categorization of COVID-19 severity to determine mortality risk
Purpose Algorithms for classification of inpatient COVID-19 severity are necessary for ...
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Real-world comparative effectiveness of mRNA-1273 and BNT162b2 vaccines among immunocompromised adults identified in administrative claims data in the United States
Introduction Head-to-head studies comparing COVID-19 mRNA vaccine effectiveness in ...
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Treatment effectiveness in a rare oncology indication: lessons from an external control cohort study
Real-world data (RWD) reflecting patient treatment in routine clinical practice can be ...
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Describing characteristics and treatment patterns of patients hospitalized with COVID-19 by race and ethnicity in a national RWD during the early months of the pandemic
Objective To describe differences by race and ethnicity in treatment patterns among ...
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A case for synthetic data in regulatory decision-making in Europe
Regulators are faced with many challenges surrounding health data usage, including ...