Blog
Privacy Assurance FAQ
What is Privacy Assurance? One of the benefits of synthetic data is that it has low ...
Blog
Synthetic Data Generation FAQ
What is synthetic data generation (SDG)? There are many ways to generate synthetic data. ...
Blog
Aetion® Generate FAQ
What is Generate? Aetion® Generate, formerly Replica Synthesis, is Aetion’s scalable ...
Publication
Prescription opioid fills following surgical abortion
Objective To characterize opioid fills after surgical abortion among US ...
Publication
Use of an EHR to inform an administrative data algorithm to categorize inpatient COVID-19 severity.
Importance Algorithms for classification of inpatient COVID-19 severity are necessary for ...
Publication
Selective serotonin reuptake inhibitor use and perioperative bleeding and mortality in patients undergoing coronary artery bypass grafting: a cohort study
Introduction Several small studies have reported inconsistent findings about the safety ...
Publication
Early real-world experience with emicizumab and concomitant factor VIII replacement products in adult male people with Hemophilia A without inhibitors
Aims To assess real-world use of emicizumab in adult people with hemophilia A (PwHA) ...
Publication
Categorization of COVID-19 severity to determine mortality risk
Purpose Algorithms for classification of inpatient COVID-19 severity are necessary for ...
Publication
Real-world comparative effectiveness of mRNA-1273 and BNT162b2 vaccines among immunocompromised adults identified in administrative claims data in the United States
Introduction Head-to-head studies comparing COVID-19 mRNA vaccine effectiveness in ...
Publication
Treatment effectiveness in a rare oncology indication: lessons from an external control cohort study
Real-world data (RWD) reflecting patient treatment in routine clinical practice can be ...
Publication
Describing characteristics and treatment patterns of patients hospitalized with COVID-19 by race and ethnicity in a national RWD during the early months of the pandemic
Objective To describe differences by race and ethnicity in treatment patterns among ...
Publication
A case for synthetic data in regulatory decision-making in Europe
Regulators are faced with many challenges surrounding health data usage, including ...
Publication
Uterine fibroids and incidence of depression, anxiety and self-directed violence: a cohort study
Background Depression and anxiety are prevalent among women with uterine fibroids (UF). ...
Publication
Graphical depiction of longitudinal study designs in health care databases
Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has become a ...
Publication
Actionable Real-World Evidence to Improve Health Outcomes and Reduce Medical Spending Among Risk-Stratified Patients with Diabetes
Background: Type 2 diabetes mellitus (T2DM) is a chronic condition with a high economic ...
Publication
Effectiveness of the Single-Dose Ad26.COV2.S COVID Vaccine
Importance Vaccination against the SARS-CoV-2 virus is critical to control the pandemic. ...
Publication
Outcomes associated with oral anticoagulants plus antiplatelets in patients with newly diagnosed atrial fibrillation
Importance Patients with nonvalvular atrial fibrillation at risk of stroke should receive ...
Publication
SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes
Importance: In the absence of evidence of clinical utility, the United States' Centers ...
Publication
Treatment Patterns and Healthcare Resource Utilization Among Newly Diagnosed Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, and Hidradenitis Suppurativa
Introduction Psoriasis (PSO), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), ...
Publication
Healthcare Resource Utilization and Related Costs in Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype: A US Claims Database Analysis
Introduction We aimed to describe healthcare resource utilization (HCRU) patterns and ...
Publication
Variable selection for confounding adjustment in high-dimensional covariate spaces when analyzing healthcare databases
Background: Data-adaptive approaches to confounding adjustment may improve performance ...
Publication
Comparison of External Control Arm Critiques in Regulatory and Health Technology Assessment of Oncology Submissions
Objectives: The development of accelerated approval programs for high morbidity and unmet ...
Publication
Erratum: high-dimensional propensity score adjustment in studies of treatment effects using health care claims data
In the article titled “High-dimensional Propensity Score Adjustment in Studies of ...
Publication
Measuring prevalence and incidence of chronic conditions in claims and electronic health record databases
Background Health care databases are natural sources for estimating prevalence and ...