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Blog
Feb 15, 2023

Privacy Assurance FAQ

What is Privacy Assurance? One of the benefits of synthetic data is that it has low ...
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Blog
Feb 15, 2023

Synthetic Data Generation FAQ

What is synthetic data generation (SDG)? There are many ways to generate synthetic data. ...
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Blog
Feb 15, 2023

Aetion® Generate FAQ

What is Generate? Aetion® Generate, formerly Replica Synthesis, is Aetion’s scalable ...
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Publication
Feb 14, 2023

Prescription opioid fills following surgical abortion

Objective To characterize opioid fills after surgical abortion among US ...
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Publication
Feb 14, 2023

Use of an EHR to inform an administrative data algorithm to categorize inpatient COVID-19 severity.

Importance Algorithms for classification of inpatient COVID-19 severity are necessary for ...
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Publication
Feb 14, 2023

Selective serotonin reuptake inhibitor use and perioperative bleeding and mortality in patients undergoing coronary artery bypass grafting: a cohort study

Introduction Several small studies have reported inconsistent findings about the safety ...
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Publication
Feb 14, 2023

Early real-world experience with emicizumab and concomitant factor VIII replacement products in adult male people with Hemophilia A without inhibitors

Aims To assess real-world use of emicizumab in adult people with hemophilia A (PwHA) ...
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Publication
Feb 14, 2023

Categorization of COVID-19 severity to determine mortality risk

Purpose Algorithms for classification of inpatient COVID-19 severity are necessary for ...
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Publication
Feb 14, 2023

Real-world comparative effectiveness of mRNA-1273 and BNT162b2 vaccines among immunocompromised adults identified in administrative claims data in the United States

Introduction Head-to-head studies comparing COVID-19 mRNA vaccine effectiveness in ...
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Publication
Feb 14, 2023

Treatment effectiveness in a rare oncology indication: lessons from an external control cohort study

Real-world data (RWD) reflecting patient treatment in routine clinical practice can be ...
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Publication
Feb 14, 2023

Describing characteristics and treatment patterns of patients hospitalized with COVID-19 by race and ethnicity in a national RWD during the early months of the pandemic

Objective To describe differences by race and ethnicity in treatment patterns among ...
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Publication
Feb 14, 2023

A case for synthetic data in regulatory decision-making in Europe

Regulators are faced with many challenges surrounding health data usage, including ...
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Publication
Feb 14, 2023

Uterine fibroids and incidence of depression, anxiety and self-directed violence: a cohort study

Background Depression and anxiety are prevalent among women with uterine fibroids (UF). ...
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Publication
Feb 14, 2023

Graphical depiction of longitudinal study designs in health care databases

Pharmacoepidemiologic and pharmacoeconomic analysis of health care databases has become a ...
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Publication
Feb 14, 2023

Actionable Real-World Evidence to Improve Health Outcomes and Reduce Medical Spending Among Risk-Stratified Patients with Diabetes

Background: Type 2 diabetes mellitus (T2DM) is a chronic condition with a high economic ...
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Publication
Feb 14, 2023

Effectiveness of the Single-Dose Ad26.COV2.S COVID Vaccine

Importance Vaccination against the SARS-CoV-2 virus is critical to control the pandemic. ...
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Publication
Feb 14, 2023

Outcomes associated with oral anticoagulants plus antiplatelets in patients with newly diagnosed atrial fibrillation

Importance Patients with nonvalvular atrial fibrillation at risk of stroke should receive ...
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Publication
Feb 14, 2023

SARS-CoV-2 spike-protein targeted serology test results and their association with subsequent COVID-19-related outcomes

Importance: In the absence of evidence of clinical utility, the United States' Centers ...
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Publication
Feb 14, 2023

Treatment Patterns and Healthcare Resource Utilization Among Newly Diagnosed Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, and Hidradenitis Suppurativa

Introduction Psoriasis (PSO), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), ...
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Publication
Feb 14, 2023

Healthcare Resource Utilization and Related Costs in Chronic Fibrosing Interstitial Lung Diseases with a Progressive Phenotype: A US Claims Database Analysis

Introduction We aimed to describe healthcare resource utilization (HCRU) patterns and ...
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Publication
Feb 14, 2023

Variable selection for confounding adjustment in high-dimensional covariate spaces when analyzing healthcare databases

Background: Data-adaptive approaches to confounding adjustment may improve performance ...
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Publication
Feb 14, 2023

Comparison of External Control Arm Critiques in Regulatory and Health Technology Assessment of Oncology Submissions

Objectives: The development of accelerated approval programs for high morbidity and unmet ...
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Publication
Feb 14, 2023

Erratum: high-dimensional propensity score adjustment in studies of treatment effects using health care claims data

In the article titled “High-dimensional Propensity Score Adjustment in Studies of ...
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Publication
Feb 14, 2023

Measuring prevalence and incidence of chronic conditions in claims and electronic health record databases

Background Health care databases are natural sources for estimating prevalence and ...
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