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Evidence Hub

Presentation
May 20, 2020

What We Learned About Data Synthesis in 2020

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Blog
May 14, 2020

FDA vaccine approval and common self-controlled study designs for vaccine safety testing

Across the United States, a patchwork of communities have begun to lift the stay-at-home ...
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Blog
May 8, 2020

HTAs and RWE: Current use, predicted trends, and next steps for biopharma

In recent years, technological advances have both expanded the amount and availability of ...
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Blog
Apr 29, 2020

Priorities for modernizing ClinicalTrials.gov: Five ideas to facilitate transparency in observational research

ClinicalTrials.gov (CT.gov) is the largest public clinical registry and results database ...
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Blog
Apr 23, 2020

Real-world evidence and COVID-19: Empower rapid, reliable, data science-driven decisions

The COVID-19 pandemic has triggered intense and widespread action among the biopharma ...
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Blog
Apr 21, 2020

The surge in RWE supported FDA approvals: A look at three FDA decisions

The U.S. Food and Drug Administration (FDA) is approving more drugs with the help of ...
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Apr 21, 2020

CBER-Approved BLA for ZOLGENSMA (onasemnogene abeparvovec-xioi)

On May 24, 2019, the FDA approved AveXis’s ZOLGENSMA® (onasemnogene abeparvovec-xioi), ...
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Apr 20, 2020

CDER-Approved NDA for LUTATHERA® (lutetium Lu 177 dotatate)

On January 26, 2018, the FDA granted approval to Advanced Accelerator Applications USA, ...
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FDA Decision Alert
Apr 20, 2020

CDER-Approved NDA for pretomanid tablets

On August 14, 2019, the FDA approved TB Alliance’s pretomanid tablets as part of a ...
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FDA Decision Alert
Apr 20, 2020

CDER-Approved NDA for SCENESSE® (afamelanotide 16mg)

On October 8, 2019, the FDA granted approval to Clinuvel Pharmaceuticals Limited’s ...
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FDA Decision Alert
Apr 20, 2020

CDER-Approved NDA for WAKIX® (pitolisant) tablets

On August 14, 2019, the FDA approved Harmony Biosciences’ WAKIX® (pitolisant) tablets, ...
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FDA Decision Alert
Apr 20, 2020

CDER-Approved NDA for EGATEN™ (triclabendazole)

On February 13, 2019, the FDA approved Novartis’ EGATEN™ (triclabendazole), which was ...
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FDA Decision Alert
Apr 20, 2020

CDER-Approved BLA for Jeuveau™ (prabotulinumtoxinA-xvfs)

On February 1, 2019, the FDA approved Evolus, Inc.’s Jeuveau™ (prabotulinumtoxinA-xvfs), ...
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Blog
Apr 16, 2020

Optimizing pharma organizational design for effective use of real-world evidence

Across the pharma product lifecycle, factors like the regulatory environment and business ...
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Blog
Apr 8, 2020

How RWE can inform cancer care: Q&A with Dr. Deb Schrag, oncologist and observational researcher

Real-world evidence (RWE) has emerged as a useful tool for industry and regulators in ...
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Blog
Apr 1, 2020

How can you leverage RWE to help advance your organization’s goals? Q&A with Dr. Yin Ho

Trained as an emergency medicine physician, Yin Ho, M.D., M.B.A., stepped out of the ...
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Blog
Mar 27, 2020

How to plan for evidence generation in a time of uncertainty

Much of my time lately has been dedicated to contemplating the magnitude of COVID-19’s ...
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Presentation
Mar 25, 2020

Empirical Assessment of Privacy Risks in Data

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Blog
Mar 20, 2020

COVID-19: Recommended readings and resources from Aetion scientists

Over the past few weeks, we’ve been adjusting to the many changes and uncertainties ...
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Blog
Mar 12, 2020

Making the business case for RWE: Julie Schiffman’s advice for biopharma on leveraging data to drive impact

How can teams within biopharma ensure their real-world evidence (RWE) studies make the ...
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Blog
Mar 5, 2020

Psychiatrist and health care CEO Dr. Gary Gottlieb: Treating the patient as a whole person

With his previous professional experience ranging from CEO of Massachusetts-based ...
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Blog
Feb 27, 2020

Aetion, Dr. Scott Gottlieb, biopharma leaders’ discussions at JPM 2020: It’s time to “knock on an open door” to further RWE standards and acceptance

This January, in the whirlwind week of the 36th Annual J.P. Morgan Healthcare Conference ...
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Blog
Feb 20, 2020

How to amplify RWE clarity and reproducibility with data visualizations: Q&A with Dr. Shirley Wang of the REPEAT initiative

While analyses of non-randomized health care databases—insurance claims, electronic ...
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Blog
Feb 20, 2020

Artificial Intelligence in Health Care - GAO Report

Benefits and Challenges of Machine Learning in Drug Development The adoption of ...
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