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May 17, 2019

Correlated or causal? Exchangeability and propensity score modeling explained

When designing comparative studies, epidemiologists aim for exchangeability between ...
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May 10, 2019

Methods, approaches, and predictions: Dr. Jessica Franklin discusses RCT DUPLICATE

Known as a “methods wiz” among her collaborators, Jessica Franklin, Ph.D., dedicates her ...
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May 3, 2019

Do real-world evidence studies require a separate registry? A conversation with Richard Willke, Ph.D., Chief Science Officer, ISPOR

As FDA intensifies its focus on real-world evidence (RWE) and the work to establish ...
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Apr 26, 2019

Future sources of real-world data: Opportunities and challenges

Today, real world data (RWD) primarily consists of administrative claims databases, ...
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Apr 20, 2019

A shared learning process: 3 takeaways from the Harvard-MIT Center for Regulatory Science’s annual meeting

Academe, U.S. Food and Drug Administration (FDA) staff, and industry leaders gathered at ...
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Apr 12, 2019

Real-world evidence use cases: A round up of essential sources of information

For those looking to learn more about real-world evidence (RWE), there is a wealth of ...
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Apr 5, 2019

A perfect data set? Yes and no: The All of Us Project

In an ideal world, all health data would be meticulously collected, capture the whole ...
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Mar 21, 2019

Real-world evidence shows that prescription amphetamine use increases risk of psychosis in ADHD

Five million people under the age of 25 in the U.S. are prescribed stimulants to treat ...
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Mar 15, 2019

Why does traceability data matter—and how do platforms help?

When considering the use of real-world evidence (RWE) for decision-making purposes, we ...
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Mar 8, 2019

The epidemiology of databases: Part III: The expanding uses of real-world evidence

Part I: Four principles of working with real-world data
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Mar 2, 2019

The perils of immortal time bias

In the early 2000s, a study published in the Annals of Internal Medicine reported that ...
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Feb 23, 2019

The epidemiology of databases: Part II: Four principles of generating real-world evidence

In a recent comment letter to the U.S. Food and Drug Administration, Aetion outlined key ...
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Feb 16, 2019

The epidemiology of databases: Part I: Four principles of working with real-world data

As the U.S. Food and Drug Administration continues its formal exploration of the use of ...
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Feb 8, 2019

Where public health and quantitative science overlap: A conversation with senior scientist Erin Comerford

Health care tech and data grab all the headlines, but science matters most. Erin ...
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Feb 1, 2019

Welcome to the Evidence Hub

At Aetion, we work at the crossroads of health care: the point at which patients, ...
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Jan 31, 2019

Framework for FDA’s Real-World Evidence Program: Dr. Sebastian Schneeweiss considers implications for biopharma

‍In December 2018, the U.S. Food and Drug Administration unveiled its strategy to assess ...
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Jan 31, 2019

Leading change at Pfizer: A conversation with Chris Boone

As costs soar and patients wait, forward-looking pharmaceutical companies are exploring ...
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Jan 31, 2019

Four questions to ask your data

A vital step in generating real-world evidence is understanding where the available data ...
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Jan 31, 2019

A year of acceleration: Looking ahead at 2019

The place where two rivers meet is called a confluence—a good word for the year ahead in ...
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