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Aetion

Blog Post by Aetion

Nov 26, 2025

Real-World Persistence in Adults with HIV and Mental Health or Substance Use Disorders After Restarting Antiretroviral Therapy in the United States

People with HIV need consistent antiretroviral therapy to maintain viral suppression and ...
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Nov 26, 2025

Considerations for emulations of randomized controlled trials using real-world data: Learnings from an emulation of MONALEESA-2

Patients treated in real-world settings may have different demographic and health ...
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Nov 11, 2025

Information Bias in Electronic Health Records and Administrative Claims Data: A Targeted Review of the Recent Literature

As real-world evidence (RWE) plays an increasingly significant role in regulatory and ...
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Oct 30, 2025

Prevalence of Diagnosed Essential Tremor in the United States: An Administrative Claims-Based Study

Essential tremor (ET) is among the most common movement disorders, yet estimates of its ...
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Oct 30, 2025

A review of methodologic & data considerations for vaccine safety surveillance in the wake of the COVID-19 pandemic

The COVID-19 pandemic tested the limits of existing vaccine safety surveillance systems, ...
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Sep 26, 2025

Evaluating the Impact of Data Standardization on Real-World Data

Standardizing real-world data (RWD) can improve consistency and reduce errors, but it may ...
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Sep 26, 2025

Combining Real-World and Clinical Trial Data Through Privacy-Preserving Record Linkage: Opportunities and Challenges—A Narrative Review

Randomized clinical trials (RCTs) and real-world data (RWD) each offer valuable ...
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Aug 7, 2025

Actions for stakeholders to develop better real-world evidence for HTA bodies/payers decision making

Real-world evidence (RWE) is essential to support decision-making by health technology ...
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Aug 4, 2025

The Product Brief: Scaling Smarter Evidence Generation in 2025

Katia Druzhynina, Pippa Hodgkins, Lucy Mosquera Driven by our mission to redefine ...
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Jul 22, 2025

Hope is Not a Strategy: Using Robust Real-World Evidence to Make Better Clinical Development Decisions

Real-world evidence (RWE) has the power to guide smarter decisions throughout the ...
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Jul 9, 2025

Built for Compliance: How Aetion® Delivers Regulatory-Grade Real-World Evidence

Nataile Schibell, MPH and Pippa Hodgkins
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Jul 8, 2025

Patti's People - Patti Peeples speaks with Jeremy Rassen

In this interview hosted by The Evidence Base, Aetion Co-Founder and CEO Dr. Jeremy ...
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Jun 5, 2025

When Clinical Trials Stall, Evidence Shouldn't: How Generative Models Restore Power to Under-Enrolled Studies

Lucy Mosquera, MS, and Natalie Schibell, MPH Understanding the Impact of Incomplete ...
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Jun 3, 2025

Real-World Evidence at Every Stage – How Aetion Powers the Drug Development Lifecycle

Natalie Schibell, MPH and Ashley Jaksa, MPH
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May 29, 2025

Built for Scientific Rigor: How Aetion Delivers Methodologically Defensible Real-World Evidence

Debra E. Irwin, PhD, MSPH, Amanda Kong, DrPH, and Natalie Schibell, MPH
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May 21, 2025

Analytic Flexibility in Focus: Using Aetion Measure Library and Substantiate in Discover

Natalie Schibell, MPH and Jaquelyn Bilog
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May 7, 2025

Real-World Evidence in Health Technology Reassessments: A New Era in Evidence-Based Decision-Making

Ashley Jaksa, MPH, and Patrick Arena, PhD A Lifecycle Approach to Evaluating the Value of ...
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May 5, 2025

From Framework to Formulary: Real-World Evidence in Action for Managed Care

Ashley Jaksa, MPH and Natalie Schibell, MPH
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Apr 30, 2025

Feature Spotlight: Streamlining Propensity Score Adjustment with Substantiate

Nataile Schibell, MPH and Pippa Hodgkins
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Apr 2, 2025

Safety and effectiveness of MVA-BN vaccination against mpox in at-risk individuals in Germany (SEMVAc and TEMVAc)

As mpox continues to pose a global public health challenge, real-world evidence (RWE) ...
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Apr 2, 2025

Increasing the Utility of Real-World Data to Inform Public Health Decision Making Through a US-based Private–Public Partnership

The urgency of the COVID-19 pandemic highlighted the need for rapid, reliable real-world ...
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Mar 27, 2025

Ensuring Accuracy in Real-World Epidemiology: How Aetion® Substantiate Delivers Reliable Prevalence and Incidence Estimates

Ashley Jaksa, MPH, Natalie Schibell, MPH, and Pippa Hodgkins Aetion® Substantiate: A ...
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Mar 24, 2025

Quantifying Disease Burden with Confidence: Prevalence and Incidence Analytics in Aetion® Discover

Natalie Schibell, MPH, Pippa Hodgkins, and Abby Case Aetion® Discover: A Solution for ...
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Mar 20, 2025

Whitepaper: Synthetic Data in Healthcare: Solving Privacy, Scarcity, and Bias Challenges

While real-world data (RWD) offers invaluable insights for research and decision-making, ...
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