In 2024, Aetion continued to redefine real-world evidence (RWE) generation by combining scientific rigor, cutting-edge technology, and operational excellence. Key milestones included the opening of Aetion’s Barcelona tech hub, an investment in global talent and innovation designed to accelerate advancements in our software capabilities. Led by Ken Watson, our Chief Technology Officer, these efforts have solidified Aetion as the industry leader in scalable, transparent, and decision-grade evidence.
With a steadfast focus on delivering reliable, reproducible results, Aetion’s advancements in 2024 positioned the Aetion Evidence Platform® (AEP) as the trusted foundation for addressing the complexities of modern healthcare decision-making. These achievements reflect our unwavering commitment to empowering stakeholders to meet today’s challenges with clarity and confidence.
Key Achievements from 2024
Performance and Operational Advancements in AEP
AEP delivered measurable improvements across critical operational metrics, ensuring reliability and efficiency for users:
- New weekly releases delivered faster updates, ensuring continuous enhancements to meet evolving research needs.
- Increased cohort and analysis job success rates enhanced confidence in outputs, even for complex studies.
- Reduced processing times accelerated study timelines, allowing researchers to generate insights faster.
Discover: Transformative Tools for Exploratory Insights
The launch of Aetion® Discover introduced AI-driven tools that redefined exploratory RWE workflows, empowering researchers with advanced capabilities to navigate large datasets:
- Smart Risk Profiles identify drivers for healthcare resource utilization (HCRU) and cost outcomes, reducing manual effort.
- Smart Subgroups automate the detection of population subsets, uncovering meaningful patterns without additional queries.
- AetionAI Smart Subgroup Interpreter enables researchers to ask targeted questions, explore subgroup dynamics in depth, and drive study progression.
- Created 15+ outcomes across clinical events, drug utilization, HCRU, and cost, offering comprehensive analytical coverage.
- New features, including Dataset Comparison for feasibility analysis and Analysis Duplication, enable users to build on existing analyses with ease.
With the launch of Discover, Aetion introduced research-aligned workflows, advanced visual analytics for interpretability, and AI-driven features. These innovations streamline exploratory data analysis, uncover complex patterns, and enable deeper inquiries, setting a new benchmark for real-world evidence generation.
Substantiate: Strengthening Evidence Integrity and Transparency
Enhancements to Aetion® Substantiate ensured it remained the trusted solution for generating regulatory-grade RWE:
- Custom Analyses enables customized workflows, supporting unique research objectives.
- AetionAI Measures Assistant accelerates study implementation by streamlining variable creation.
- Direct access to past dataset revisions and separate analytic cohort file generation enhances transparency and reproducibility.
- Productivity enhancements such as multi-cohort workflows and bulk editing advanced operational efficiency while maintaining scientific rigor.
- Customizable visualizations enhances communication of findings by allowing outputs to align with organizational brand guidelines, aligning results with stakeholder expectations.
These updates continue to solidify Substantiate’s role as the critical tool for delivering rigorous evidence that meets the highest scientific and regulatory standards.
Generate: Privacy-Centric Innovations for Synthetic Data
In 2024, Aetion relaunched Replica Synthesis as Aetion® Generate, introducing significant advancements to balance responsible data access with rigorous privacy protections:
- Partial longitudinal synthesis expands synthetic data generation for complex datasets, preserving analytical utility while safeguarding privacy.
- Self-service de-identification tools simplifies compliance workflows, offering greater flexibility for sensitive data management.
- Multi-table risk assessments addresses privacy concerns across large datasets, providing scalable solutions for enterprise needs.
- Enhanced handling of many quasi-identifiers simultaneously ensures comprehensive and efficient risk measurement for complex data.
- Operational features like job cancellation and user admin tools streamline workflow management and improve scalability.
Generate’s innovations reinforced its position as a leader in privacy-enhancing technologies (PETs), empowering researchers to navigate data challenges securely and effectively.
Looking Ahead: 2025 Roadmap
Building on the successes of 2024, Aetion’s 2025 priorities center on advancing researcher capabilities, enhancing interoperability, and advancing real-world evidence (RWE) generation through the following initiatives:
- Advanced Cohort Design and Analytics in Activate: The NEW Activate application will support advanced cohort design and analytics workflows tailored for biostatisticians and data scientists. With seamless interoperability across Aetion’s existing applications, Activate will bridge no-code and code-based users, fostering collaboration and optimizing RWE generation.
- EHR Dataset Integration in Discover: Discover’s exploratory capabilities will expand with the integration of new data types, including EHR and lab data. These additions enable researchers to uncover deeper insights and conduct robust, comprehensive data analyses.
- Enhanced Privacy Tools in Generate: Generate will introduce advancements in risk assessment and de-identification workflows, bolstering privacy protections for large-scale studies. These scalable tools ensure secure, compliant analytics while maintaining data integrity.
- Self-Service User Permissioning and Authentication: New self-service features will enhance user autonomy, providing organizations with greater control and flexibility in managing access across applications and streamlining workflows.
These initiatives reflect Aetion’s dedication to addressing emerging demands in evidence generation and setting the standard for innovation in 2025 and beyond.
2024 at a Glance
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Domain
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Application
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Key Advances
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Accelerated Performance
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Platform-wide
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- Faster queries and job execution streamline workflows
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- Higher success rates deliver reliable results for complex studies
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- New weekly releases enable rapid, continuous enhancements
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AI-Driven Insights
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- Smart Risk Profiles uncover drivers of healthcare costs and resource utilization
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- Smart Subgroups automate meaningful population pattern detection
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- AI-powered tools drive deeper exploration and actionable insights
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Breakthrough Features
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- Custom Analyses tailors workflows to unique research needs
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- Multi-cohort workflows and regulatory-grade visuals improve study precision and clarity
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- 15+ outcome types expand analytical capabilities
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- Dataset Comparison and Analysis Duplication optimize exploratory workflows
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- Self-service de-identification simplifies privacy compliance
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Next-Level Privacy
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- Synthetic data preserves privacy and retains analytical utility
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- Scalable risk assessments protect multi-dimensional datasets
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- Partial longitudinal synthesis advances synthetic data for complex applications
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- User admin tools simplify workflow management and enhance stability
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Aetion: Leading the Evolution of Evidence Generation
Through its unwavering commitment to rigorous science, trusted technology, and operational excellence, Aetion remains a reliable and innovative partner in shaping the future of healthcare decision-making. The Aetion Evidence Platform® enables stakeholders to derive decision-grade findings, transforming complex data into transparent, scientifically rigorous results that drive informed healthcare decisions.
As we enter 2025, Aetion stands poised to lead the evolution of real-world evidence, enabling healthcare leaders to navigate complexity with confidence and deliver transformative outcomes for patients worldwide.
Learn how our advanced analytics, AI-driven tools, and privacy-centric solutions can help you navigate complex healthcare challenges by requesting a demo today.